You can uninstall or removes an installed libdigest-perl-md5-perl package itself from Ubuntu 16.10 (Yakkety Yak) through the terminal,
$ sudo apt-get remove libdigest-perl-md5-perl
If you would like to remove libdigest-perl-md5-perl and it's dependent packages which are no longer needed from Ubuntu,
$ sudo apt-get remove --auto-remove libdigest-perl-md5-perl
If you use with purge options to libdigest-perl-md5-perl package all the configuration and dependent packages will be removed.
$ sudo apt-get purge libdigest-perl-md5-perl
If you use purge options along with auto remove, will be removed everything regarding the package, It's really useful when you want to reinstall again.
$ sudo apt-get purge --auto-remove libdigest-perl-md5-perl